Radioembolization with Yttrium-90 Microspheres (SIRT) in Pancreatic Cancer Patients with Liver Metastases: Efficacy, Safety and Prognostic Factors
نویسندگان
چکیده
منابع مشابه
Radioembolization with yttrium-90 microspheres for pancreatic cancer liver metastases: results from a pilot study.
BACKGROUND Patients with liver metastases from pancreatic adenocarcinomas have a dismal prognosis. Surgical resection remains the only curative option but is appropriate for only a minority of patients as a treatment option. This is the first study to examine the safety and efficacy of radioembolization with yttirum-90 microspheres for these patients. PATIENTS AND METHODS All patients with hi...
متن کاملYttrium-90 Radioembolization for Pancreatic Neuroendocrine Liver Metastases
Background: Management options for pancreatic neuroendocrine tumors (pNETs) metastatic to the liver include surgical, ablative, cytotoxic, and radioisotope approaches. One potential local treatment option includes selective internal radiotherapy utilizing yttrium-90 ( 90 Y) microspheres. 90 Y has also been used in the treatment of hepatocellular carcinoma and tumors metastatic to the liver. It ...
متن کاملRadioembolization of liver tumors with yttrium-90 microspheres.
Radioembolization (RE), also termed selective internal radiation therapy (SIRT), has been gradually introduced to the clinical arsenal of cytoreductive modalities in recent years. There is growing evidence for efficiency in liver tumors of various entities, with the most prominent ones being hepatocellular carcinoma, colorectal cancer, and neuroendocrine tumors. Hepatic metastases of numerous o...
متن کاملRadioembolization with yttrium-90 resin microspheres for neuroendocrine tumor liver metastases.
PURPOSE We aimed to evaluate the effectiveness and safety of radioembolization with yttrium-90 (90Y) microspheres in cases with unresectable neuroendocrine tumor liver metastases (NETLMs). METHODS Thirty patients (mean age, 55 years) underwent resin-based 90Y radioembolization for unresectable NETLM at a single institution between April 2008 and June 2013. Post-treatment tumor response was as...
متن کاملInternal dosimetry for radioembolization therapy with Yttrium‐90 microspheres
The absorbed doses in the liver and adjacent viscera in Yttrium-90 radioembolization therapy for metastatic liver lesions are not well-documented. We sought for a clinically practical way to determine the dosimetry of this advent treatment. Six different female XCAT BMIs and seven different male XCAT BMIs were generated. Using Monte Carlo GATE code simulation, the total of 100MBq 90 Y was depos...
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ژورنال
عنوان ژورنال: Oncology
سال: 2014
ISSN: 1423-0232,0030-2414
DOI: 10.1159/000355821